What is hemolysis index?

Hemolysis index refers to the degree of red blood cell (RBC) destruction or lysis caused by different factors, such as drugs, chemicals, or medical devices. The hemolysis index is measured by the amount of hemoglobin released from the lysed RBCs in the blood. A high hemolysis index indicates greater RBC destruction and can lead to anemia, jaundice, and organ damage. Hemolysis index is an important parameter in clinical studies and medical device evaluation to ensure the safety and compatibility of these products with human blood. Various analytical methods are used to measure hemolysis index, including spectrophotometric and colorimetric assays.